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Report | Regular issue | Vol 23, No. 6, 1985, pp.1437-1444
Published online, 1st January, 1970
DOI: 10.3987/R-1985-06-1437
Phosphorus Pentoxide in Organic Synthesis - Part 23. Synthesis of 1,2,3,4-tetrahydro-9-acridinamines

Peter Finlander, Hans Peter Fischer, and Erik Bjerregaard Pedersen*

*Department of Chemistry, Odense University, Campusvej 55 DK-5230 Odense M., Denmark


1,2,3,4-Tetrahydro-9(10H)-acridinone 2 was synthesized from methyl anthranilate and cyclohexanone using a mixture of P2O5 and N,N-dimethylcyclohexylamine as a condensing reagent. 1,2,3,4-Tetrahydro-9-acridinamines 3 were prepared, either directly from 2, using the new phosphoric amide reagents, or via the corresponding 9-chloro derivative 7 by reaction with amines.