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Report | Regular issue | Vol 23, No. 3, 1985, pp.633-639
Published online, 1st January, 1970
DOI: 10.3987/R-1985-03-0633
Synthesis of α-Hydroxydimethylacetals from Nitrogen Heterocyclic Ketones Using Hypervalent Iodine Oxidation

Robert M. Moriarty,* Om Prakash, Cyriac T. Thachet, and Hikmat A. Musallam

*Department of Chemistry, University of Illinois at Chicago, 845 West Taylor St., Chicago, IL 60607-7061, U.S.A.

Abstract

The synthesis of various α-hydroxydimethylacetals (2a-2j) has been achieved by the oxidation of nitrogen containing heterocyclic ketones (1a-1j) using C6H5I(OAc)2-KOH-MeOH . The nmr and mass spectra of the acetals are discussed.