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Communication | Regular issue | Vol 23, No. 2, 1985, pp.291-293
Published online, 1st January, 1970
DOI: 10.3987/R-1985-02-0291
Reaction of Chromone Epoxides. I. Reaction of 2,3-Epoxyisoflavone with Alkylamines

Ichiro Yokoe,* Kumiko Nakamura, Kyoko Higuchi, Yoshiaki Shirataki, Manki Komatsu, and Hiroshi Miyamae

*Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan


The reaction of 2,3-epoxyisoflavone (1) with primary alkylamines gave 2’-hydroxy-[1-phenyl-1-(N-formyl)alkyiamino]acetophenones (2a- d), whose structures were determined on the basis of spectroscopic properties and X-ray Crystallographic analysis for N-propyl derivative (2c).