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Report | Regular issue | Vol 23, No. 1, 1985, pp.143-151
Published online, 1st January, 1970
DOI: 10.3987/R-1985-01-0143
The Facile One Pot Synthesis of 6-Substituted 2(1H)-Quinoxalinones

Gozyo Sakata,* Kenzi Makino, and Katsushi Morimoto

*Central Research Institute, Nissan Chemical Industries Ltd., 722-1 Tsuboicho, Funabashi, Chiba 274-8507, Japan


Facile one pot synthesis of 6-substituted 2(1H)-quinoxalinones and these reaction mechanisms are described. The intramolecular cyclization reaction of 4’-substituted 2’-nitroacetoacetanilides in aqueous basic medium and the reduction of 6-substituted 2(1H)-quinoxalinone-4-oxide with sodium borohydride or sodium hydrogensulfite were studied in detail.