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Report | Regular issue | Vol 23, No. 1, 1985, pp.111-116
Published online, 1st January, 1970
DOI: 10.3987/R-1985-01-0111
Heterocycles. XVI. Methylation of the Cyclic Enamino Ketones

Masayuki Onda,* Yasumasa Sugama, and Reiko Yabuki

*School of Pharmaceutical Sciences, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8641, Japan


Methylation of the tetrahydrobenzo[a]quinolizinone 2 and the dihydrobenzo[a]quinolizinone 3 has been examined. The regioselectivity at the nitrogen and oxygen atoms is tremendously affected by the solvents.