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Report | Regular issue | Vol 22, No. 8, 1984, pp.1789-1790
Published online, 1st January, 1970
DOI: 10.3987/R-1984-08-1789
A Synthesis of Carbamic Acid [Imidazo-heteroaromatic] Methyl Ester Derivatives Using Methoxycarbonyl Isothiacyanate

Siya Ram, Dean S. Wise, and Leroy B. Townsend*

*Department of Medical Chemistry, College of Pharmacy, University of Michigan , 930 North University, Ann Arbor, MI 48109-1055, U.S.A.


Methoxycarbonyl isothiocyanate (1), in the presence of N,N-dicyclohexylcarbodiimide, has been found to be a versatile reagent for the one-pot synthesis of a bicyclic imidazo-heteroaromatic system.