Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Report | Regular issue | Vol 22, No. 8, 1984, pp.1741-1746
Published online, 1st January, 1970
DOI: 10.3987/R-1984-08-1741
1,2,3,4-Tetrahydro-1,2-diazepine Derivatives from Isoxazolo[3,4-d]pyridazin-7(6H)-ones

Vittorio Dal Piaz,* Giovanna Ciciani, Annarella Costanzo, Gabriella Auzzi, and Stefano Chimichi

*Dipartimento di Scienze Farmaceutiche, Università di Firenze, Via Gino Capponi 9, I-50121 Firenze, Italy


Treatment of isoxazolo[3,4-d]pyridazin-7(6H)-ones (2a-f) with alkali give rise to the new 6-cyano-2,3-disubstituted 1,2,3,4-tetrahydro-5H-1,2-diazepin-5-one derivatives (5a-f) through Michael type addition.