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Communication | Regular issue | Vol 22, No. 8, 1984, pp.1725-1726
Published online, 1st January, 1970
DOI: 10.3987/R-1984-08-1725
New Short Step Synthesis of 3-Hydroxyethy-4-cyanoazetidin-2-one Derivative: A Potential Precursor of the Penems and the Carbapenems

Masao Shiozaki,* Hiroshi Maruyama, and Noboru Ishida

*Chemical Research Laboratories and Analytical & Metabolic Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan


3-Hydroxyethyl-4-cyanoazetidin-2-one derivative was synthesized from (2R,3R)-2,3-epoxybutyric acid in two steps.