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Communication | Regular issue | Vol 22, No. 8, 1984, pp.1719-1723
Published online, 1st January, 1970
DOI: 10.3987/R-1984-08-1719
On the Stereochemistry of Carbonyl Substitutents at the 8-Position in the Lysergic Acid Derivatives and Their Despyrrole Analogs

Toshiko Kiguchi, Chiyomi Hashimoto, Takeaki Naito, and Ichiya Ninomiya*

*Kobe Women’s College of Pharmacy, Motoyamakita, Higashinad, Kobe, Hyogo 658, Japan


The isomerization of the carbonyl substituents at the 8-position in some despyrrololysergic acid derivatives was discovered and stereochemical studies on the configuration of the 8-substituents and on the conformation of ring D in the lysergic acid derivatives and their despyrrole analogs were also carried out.