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Communication | Regular issue | Vol 22, No. 5, 1984, pp.1013-1015
Published online, 1st January, 1970
DOI: 10.3987/R-1984-05-1013
Imidazo[2,1-b]benzothiazole. Nucleophilic Substitution Reaction on Sulfur by n-Butyl Lithium

Toshiyasu Mase and Kiyoshi Murase*

*Central Research Laboraories, Yamanouchi Pharmaceutical Co., Ltd., 1-1-8, Azusawa, Itabashi-ku, Toyko 174-0051, Japan


The nucleophilic substitution reaction on sulfur of 2-(p-methoxyphenyl)-7-methylimidazo[2,1-b]benzothiazole by n-butyl lithium affords the C-S bond cleaved compound in excellent yield.