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Communication | Regular issue | Vol 22, No. 5, 1984, pp.993-995
Published online, 1st January, 1970
DOI: 10.3987/R-1984-05-0993
Cocsuline-N-2-Oxide, a New Alkaloid from Cocculus hirsutus DC

Abdel O. El-Shabrawy, Paul L. Schiff, Jr., David J. Slatkin,* B. Das Gupta, Anil B. Ray, and Vyas J. Tripathi

*Department of Pharmacognosy, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, U.S.A.

Abstract

Chromatography of an ethanol extract of Cocculus hirsutus DC. (Menispermaceae) over silicic acid afforded a new bisbenzylisoquinoline alkaloid, cocsuline-N-oxide (1). The alkaloid was characterized by a consideration of its physicochemical data and conversion to cocsuline (2).