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Report | Regular issue | Vol 22, No. 2, 1984, pp.353-354
Published online, 1st January, 1970
DOI: 10.3987/R-1984-02-0353
Heterosysles in Organic Synthesis. Part VI — A Facile Synthesis of 1-(4-Aryl-2-thiazolyl)-2-propanones

Harjit Singh,* Sunil K. Aggarwal, and Nageshwar Malhotra

*Department of Chemistry, Guru Nanak Dev University, Amritsar -143 005, Punjab, India


Reactions of ω-(6-methyl-4-pyrimidinylthio)acetophenones (1) with aq. HCl/HClO4 or POCl3 followed by hydrolysis provide 1-(4-aryl-2-thiazolyl)-2-propanones (3).