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Communication | Regular issue | Vol 22, No. 2, 1984, pp.281-286
Published online, 1st January, 1970
DOI: 10.3987/R-1984-02-0281
Bis Heteroannulation. 6. The First Example of a Deils-Alder Reaction Involving a Thiazole Ring with an Acetylenic Dienophile. Geometrical Control of Reaction Pathway

Peter A. Jacobi,* Kim T. Weiss, and Melissa Egbertson

*Hall-Atwater Laboratories, Wesleyan University, Middletown, Connecicut 06459-0180, U.S.A.


Acetylenic thiazoles of proper design have been shown to undergo an intramolecular Diels-Alder reaction leading directly to fused-ring thiophene derivatives.