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Review | Regular issue | Vol 22, No. 1, 1984, pp.195-221
Published online, 1st January, 1970
DOI: 10.3987/R-1984-01-0195
The Leimgruber-Batcho Indole Synthesis

Robin D. Clark and David B. Repke

*Institute of Organic Chemistry, Syntex Research, Palo Alto, California 94304, U.S.A.


The Leimgruber-Batcho indole synthesis, which involves the reduction of β-dimethylamino-2-nitrostyrenes, is reviewed along with applications and modifications thereof.