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Communication | Regular issue | Vol 22, No. 1, 1984, pp.33-38
Published online, 1st January, 1970
DOI: 10.3987/R-1984-01-0033
Biotransformation of the 13-Hydroxytetrahydroprotoberberine N-Methyl Salts by Callus Cultures of Corydalis Species

Kinuko Iwasa,* Akiko Tomii, and Narao Takao

*Kobe Pharmaceutical University, Motoyamakita, Higashinada, Kobe 658-8558, Japan


Each N-methyl salt of trans- and cis-13-hydroxytetrahydroprotoberberines, ophiocarpine and epiophiocarpine, was biotransformed via corresponding protopine-type alkaloid into a benzindanoazepine.