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Communication | Regular issue | Vol 20, No. 11, 1983, pp.2141-2144
Published online, 1st January, 1970
DOI: 10.3987/R-1983-11-2141
A Novel Synthesis of Quinazolines and 1,4-Benzodiazepines

Jan Bergman, Anna Brynolf, and Björn Elman

*Department of Organic Chemistry, Royal Institute of Technology, SE-100 44 Stockholm, Sweden


The synthesis of 1,4-benzodiazepines and quinazolines from o-aminobenzonitriles is reported. For the formation of the 1,4-benzodiazepines a mechanism involving an intermediate aziridinone is proposed.