Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Report | Regular issue | Vol 20, No. 10, 1983, pp.2019-2023
Published online, 1st January, 1970
DOI: 10.3987/R-1983-10-2019
Synthesis and Structure of Some 1-(2-Thienylmethyl)-1H-imidazole Derivatives as Potential Antimicrobial Agents

Elena Belgodere, Ricardo Bossio, Stefano Chimichi, Stefano Marcaccini, and Roberto Pepino

*CNR, Centro di Studio Sulla Chimica e la Struttura dei Composti Eterociclici e lolo Applicazioni, c/o Dipartimento di Chimica Organica “Ugo Schiff”, Università di Firenze, Via Gino Capponi 9, I-50121 Firenze, Italy

Abstract

A series of 1-(2-thienylmethyl)-1H-imidazole derivatives were synthesized starting from 2-thienylmethylamine (I) and ethyl chloroacetate. The structure of all the new compounds were determined by uv, ir, and 1H-nmr spectroscopy. Preliminary tests of biological activity on these compounds showed that 1-(2-thienylmethyl-1H-imidazole-5-carbohydroxamic acid (XII) is fairly active against Escherichia Coli and Bacillus Subtilis.