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Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
has passed away on January 9, 2023 at the age of 85.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
January 13, 2023
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Communication | Regular issue | Vol 20, No. 10, 1983, pp.1969-1973
Published online, 1st January, 1970■ A Synthesis of Mixed Tetrahydroisoqunoline Dimers via p-Quinol Acetate
Published online, 1st January, 1970
DOI: 10.3987/R-1983-10-1969
■ A Synthesis of Mixed Tetrahydroisoqunoline Dimers via p-Quinol Acetate
Hiroshi Hara, Masatoshi Murakata, Osamu Hoshino, Bunsuke Umezawa, and Yoichi Iitaka
*Faculty of Pharmaceutical Sciences, Science University of Tokyo, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
Abstract
Several mixed tetrahydroisoquinoline dimers (4, 6, 7, 10b, 11b, 12b, and 13b) were prepared by reaction of the p-quinol acetate (1a) and the corresponding phenolic tetrahydroisoquinolines. In the case of 5-hydroxytetrahydroisoquinoline (14), a different kind of dimer (16) was obtained together with 15. A radical mechanism was presented for these reactions.
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