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Communication | Regular issue | Vol 20, No. 10, 1983, pp.1957-1958
Published online, 1st January, 1970
DOI: 10.3987/R-1983-10-1957
Synthetic Approach to the Antitumor Antibiotic Lavendamycin: a Synthesis of Demethallavendamycin Methyl Ester

Satoshi Hibino, Miko Okazaki, Kohichi Sato, Itsuko Morita, and Masataka Ichikawa

*Graduate School of Pharmacy and Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Hiroshima 729-0292, Japan

Abstract

A synthetic approach to the lavendamycin has been achieved by a formation of β-carboline derivative and oxidation of bromophenol derivative to the quinolinequinone system using cerium ammonium nitrate.