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■ Structure of Mahuannin C, a Hypotensive Principle of Ephedra Roots

Yoshimasa Kasahara, Nobuyoshi Shinomiya, Chohachi Konno, and Hiroshi Hikino

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

A new bisflavanol, mahuannin C, showing the hypotensive activity has been isolated from the crude drug “mao-kon”, the roots of Ephedra plants. The stereostructure of mahuannin C has been deduced as shown in formula I on the basis of chemical and physical evidence.