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Report | Regular issue | Vol 20, No. 6, 1983, pp.1067-1070
Published online, 1st January, 1970
DOI: 10.3987/R-1983-06-1067
Reactions of Creatone (2-Methylamino-1H-imidazole-4,5-dione)

Hiroshi Yamamoto, Toshihiro Takahashi, and Saburo Inokawa

*Department of Chemistry, Faculty of Science, Okayama University, 3-1-1 Tsushima-naka, Okayama 700-8530, Japan


Creatone (3) reversibly gives (3-methylguanidino)glyoxylic acid (6) and its ethyl ester (7) on heating with water and ethanol, respectively. These ring-opened compounds are important intermediates during the formation of creatone from creatine (1) and various other starting materials.