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■ Structure of Sanggenon G, a New Diels-Alder Adduct from the Chinese Crude Drug “Sang-Bai-Pi” (Morus Root Barks)

Toshio Fukai, Yoshio Hano, Tomoko Fujimoto, and Taro Nomura

*Faculty of Pharmaceutical Sciences, Toho University, 2-2-1, Miyama, Funabashi, Chiba 274-8510, Japan

Abstract

From the methanol extract of the Chinese crude drug “Sang-Bai-Pi” (Japanese name Sohakuhi), root barks of Morus sp. (Moraceae), a new flavanone derivative with a fused dihydrochalcone partial moiety was isolated and named sanggenon G. The structure was shown to be I on the basis of spectral data. Sanggenon G (I) is regarded biogenetically as a Diels-Alder adduct of a chalcone derivative and dehydrogeranylflavanone derivative.