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Communication | Regular issue | Vol 20, No. 4, 1983, pp.601-605
Published online, 1st January, 1970
DOI: 10.3987/R-1983-04-0601
■ Application of the Oxygenative Nucleophile Introduction Reaction to 1-Alkoxycarbonyl-2-alkynyl-1,2-dihydropyridines. A Facile Synthesis of (±)-Sedacryptine

Mitsutaka Natsume and Masashi Ogawa

*Research Foundation Itsuu Laboratory, 2-28-10 Tamagawa, Setagaya-ku, Tokyo 158, Japan

Abstract

A Sedum alkaloid, (±)-sedacryptine (17) was effectively synthesized from the compound (3g), one of the products (3a-31) derived from 2-alkynyl-1,2-dihydropyridine derivatives (2) by application of our oxygenative nucleophile introduction reaction.