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Communication | Regular issue | Vol 20, No. 4, 1983, pp.571-574
Published online, 1st January, 1970
DOI: 10.3987/R-1983-04-0571
Reinvestigation of a Recent 1,3,4-Benzotriazepine Synthesis, Formation of 1,3,4-Oxadiazoles

Endre Tihanyi, Melinda Gál, and Péter Dvoetsák

*Institute for Drug Research Ltd., H-1325 Budapest, POB 82, Hungary


It was shown by spectrosopic and synthetic methods that the reaction of anthranilic acid hydrazides with 1,1’-carbonylbisimidazole (CO/Im/2) afforded, in contrast with earlier literature data, no 1,3,4-benzotriazepines or quinazolines but 1,3,4-oxadiazole derivatives.