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Report | Regular issue | Vol 20, No. 2, 1983, pp.247-254
Published online, 1st January, 1970
DOI: 10.3987/R-1983-02-0247
Novel Conformational Effects of the N-Benzyloxycarbonyl-cis-3a-aryl-octahydroindole Nucleus. Formal Total Synthesis of Racemic Elwesine and Epielwesine

Ignacio H. Sánchez, Francisco J. López, Humberto J. Flores, and María Isabel Larraza

*Facultad de Química, Universidad Nacional Autónama de México, Circuito Exterior, Ciudad Universitaria, Coyoacán 04510, Mexico

Abstract

The formal total synthesis of racemic elwesine (I) and epielwesine (II) is described. The preferred ground-state conformation of the cis-3a-aryl-octahydroindole precursors is shown to be dependant on the substituent on nitrogen.