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Report | Regular issue | Vol 20, No. 1, 1983, pp.33-38
Published online, 1st January, 1970
DOI: 10.3987/R-1983-01-0033
Tetracyclic Phenothiazines. X. Lithiation of Pyrrolo[3,2,1-kl]phenothiazine

Torsten Dahlgren, Anders Hallberg, and Arnold R. Martin

*Department of Pharmaceutical Sciences, College of Pharmacy, The University of Arizona, Tucson, AZ 85721, U.S.A.


The lithiation of pyrrolo [3,2,1-kl] phenothiazine and subsequent reactions of the lithio intermediates giving 1- and 10-mono- and 1,10-disubstituted derivatives are reported. The reaction sites were determined from decoupled 1H and 13C NMR spectra.