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Report | Regular issue | Vol 19, No. 10, 1982, pp.1889-1894
Published online, 1st January, 1970
DOI: 10.3987/R-1982-10-1889
Oxides of Heterocyclic Quinones. N-Oxides and Epoxides of Quinoline- and Isoquinoline-5,8-dione

Jacek Mlochowski, Krystian Kloc, and Joanna Piatkowska

*Institute of Organic Chemistry, Biochemistry and Biotechnology, Wroclaw University of Technology, Wyb. Wyspianskigo 27, 50-375 Wroclaw, Poland

Abstract

The syntheses of 6,7-epoxides and N-oxides of quinoline- and isoquinoline-5,8-diones and of their 6,7-dichloro derivatives are described. The key step of synthesis is oxidation of quinoline or isoquinoline N-oxides bearing the hydroxy or amino groups in the position 5 and 8.