Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 19, No. 9, 1982, pp.1597-1604
Published online, 1st January, 1970
DOI: 10.3987/R-1982-09-1597
Synthesis of New Oxapenams and Carbapenams

Kapa Prasad and Peter Stütz

*Sandoz Research Institute, A-1235 Vieena, Austria


Diazoketones derived from 4-thioazetidinon-1-yl-acetic acids, on metal-catalysed decomposition, gave either carbapenams and/or oxapenams depending upon the nature of the substituent present on the thio function. Synthesis of a novel oxapenam carboxylic acid 16 which exhibited potent β-lactamase inhibitory properties comparable to clavulanic acid is described.