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Communication | Regular issue | Vol 19, No. 5, 1982, pp.815-818
Published online, 1st January, 1970
DOI: 10.3987/R-1982-05-0815
A General Synthesis of Indolo[2,3-a]quinolizine from a Symmetrical Starting Material, cis4-Tetrahydrophthalic Acid Anhydride

Tetsuji Kametani, Toshio Suzuki, Shinko Kamada, and Katsuo Unno

*Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan


A general synthesis of indolo[2,3-a]quinolizine derivatives (12) and (13) has been achieved by a condensation of tryptamine with the aldehyde (11) derived from a symmetrical starting material, cis4-tetrahydrophthalic acid anhydride (2).