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Communication | Regular issue | Vol 19, No. 4, 1982, pp.653-656
Published online, 1st January, 1970
DOI: 10.3987/R-1982-04-0653
Synthesis of Dihydroisoquinolines and 1-Substituted Tetrahydroisoquinolines

Frank E. Scully, Jr. and John J. Schlager

*Department of Chemical Sciences, Old Dominion University, Norfolk, Virginia 23508, U.S.A.


A simple synthesis of three dihydroisoquinolines and five 1-substituted tetrahydroisoquinolines from the parent compound involves N-chlorination/dehydrochlorination with KO2 and subsequent organometallation.