HETEROCYCLES

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

■ On Cardioactive Steroids VI. The Synthesis of 17α-Methyl Cardenolides

Karnail S. Atwal, Soumya P. Sahoo, Thomas Y. R. Tsai, and Karel Wiesner

*Natural Products Research Center, Department of Chemistry, University of New Brunswick, Bag Service #45222, Fredericton, New Brunswick, E3b 5A3, Canada

Abstract

Two methods for the simple synthesis of the Δ^14,15-17α-methyl cardenolide 1 are disclosed. This material may be functionalized to a variety of 17α-methyl derivatives for pharmacological testing. As an example, the preparation of 17α-methyl digitoxigenin 20 is described.