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Report | Regular issue | Vol 19, No. 3, 1982, pp.535-537
Published online, 1st January, 1970
DOI: 10.3987/R-1982-03-0535
Studies on the Syntheses of Heterocyclic and Natural Products. Part 968. Racemization Reaction in Bischler-Napieralski Cyclization: Synthesis of β-Carboline and Isoquinoline Nuclei from L-Tryptophan and L-Phenylalanine Derivatives

Tetsuji Kametani, Nanami Takagi, Naoaki Kanaya, and Toshio Honda

*Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan


The Bischler-Napieralski type of cyclization of L-N-acetyltryptophan methyl ester and L-N-acetyl-3,4-dimethoxyphenylalanine methyl ester in order to obtain 3,4-dihydro-9H-pyrido[3,4-b]indole and 3,4-dihydroisoquinoline derivatives has been investigated.