Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 19, No. 3, 1982, pp.473-476
Published online, 1st January, 1970
DOI: 10.3987/R-1982-03-0473
Mannich Cyclization Involcing the α-Position of Ketals: Synthesis of 2-Arly-4-piperidonesnand 2-Aryl-3-acylpyrrolidines

Joan Bosch, Mario Rubiralta, and Montserrat Moral

*Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, Av. de Joan XXIII, s/n, 08028 Barcelona, Spain


A new method for the preparation of 2-aryl-4-piperidones and 2-aryl-3-acylpyrrolidines based on the acid-induced intramolecular cyclization between an iminium salt and the α-position of a ketal group is reported.