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Communication | Regular issue | Vol 19, No. 3, 1982, pp.469-472
Published online, 1st January, 1970
DOI: 10.3987/R-1982-03-0469
Synthesis of 32-Crown-8 Tetraester Compound: Model of Macrotetrolid Antibiotics

André Samat, Mohammed El Malouli Bibout, and José Elguéro

*Laboratoire de Chimie Moléculaire et Péttoléochimie, associé au C. N. R. S., Université d’Aix-Marseille II, rue H. Poincaré, 13397 Marseille Cedex 13, France


A simple synthesis of a new thirty two membered macrocycle including height oxygen atoms (four ether, four esters) is described. This campound is a structural model of macrotetrolid nactins (ionophorous natural antibiotics)