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Report | Regular issue | Vol 19, No. 1, 1982, pp.89-90
Published online, 1st January, 1970
DOI: 10.3987/R-1982-01-0089
Synthetic Studies on β-Lactam Antibiotics: Conversion of 2-Pyridone into Azetidin-2-one

Tetsuji Kametani, Tomoko Mochizuki, and Toshio Honda

*Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan


Azetidin-2-one (4), bearing a functionalized carbon atom at the C4-position, was efficiently synthesized from 2-pyridone (1) by photolysis, followed by ozonolysis.