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Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
has passed away on January 9, 2023 at the age of 85.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
January 13, 2023
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Communication | Regular issue | Vol 16, No. 12, 1981, pp.2115-2119
Published online, 1st January, 1970■ Reaction of o-Ethoxalylaminonitriles with Cyanomethylene Compounds in the Presence of Cyanide Ion
Published online, 1st January, 1970
DOI: 10.3987/R-1981-12-2115
■ Reaction of o-Ethoxalylaminonitriles with Cyanomethylene Compounds in the Presence of Cyanide Ion
Yukihiko Tomioka and Motoyoshi Yamazaki*
*Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan
Abstract
When 2-ethoxalylaminonaphthalene-1-carbonitrile (I) was treated with potassium cyanide and some cyanomethylene compounds, such as ethyl and methyl cyanoacetates, α-cyanoacetamide and 1-cyanoacetylpyrrolidine, the corresponding 1-aminobenzo[f]quinazolines (IVa - IVd) were obtained.
Similarly, 6-ethoxalylaminoquinoline-5-carbonitrile (II) and 2-ethoxalylaminobenzonitrile (III) gave the corresponding 1-aminopyrido[3,2-f]quinazolines (Va - Vd) and 4-aminoquinazolines (VIa - VId), respectively.
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