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Communication | Regular issue | Vol 16, No. 12, 1981, pp.2109-2114
Published online, 1st January, 1970
DOI: 10.3987/R-1981-12-2109
Stereoselective Reduction of 1,2,3,4,6,7,12,12b-Octahydroindolo[2,3-a]quinolizine with Sodium Borohydride in Trifluoeoacetic Acid

Gordon W. Gribble,* Jerry L. Johnson, and Mark G. Saulnier

*Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03775, U.S.A.


The sodium borohydride/trifluoroacetic acid reduction of the title alkaloid (1) is highly stereoselective, giving the all-cis product 2 in excellent yield.