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Report | Regular issue | Vol 16, No. 11, 1981, pp.1955-1962
Published online, 1st January, 1970
DOI: 10.3987/R-1981-11-1955
Studies of Potential Heterocyclic Sulfones as Antimicrobial Agents. Synthesis and Antimicrobial Activity of Some Novel Substituted Arylsulfonylbenzo[h]quinoline Derivatives

Rajendra Prasad Bahuguna, Yogesh Chandra Joshi, Mahaveer Prasad Dobhal, Bhuwan Chandra Joshi,* and Hari Narain Mangal

*Department of Chemistry, University of Rajasthan, Jaipur 302 004, India


A series of substituted arylthiobenzo[h]quinoline (sulfides, Ia~If and IIa~IIc) synthesised earlier were oxidised (with 1% KMnO4) to get their corresponding sulfones (IA~IF and IIA~IIC). All these compounds have been characterised by their elemental analysis, molecular weight determination (Rast Method) and spectral studies (IR and 1H NMR). These compounds have been screened for antimicrobial activity against Gram positive Cocci and Gram negative Bacilli.