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Obituary
Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Communication | Regular issue | Vol 16, No. 10, 1981, pp.1651-1658
Published online, 1st January, 1970■ Substitutent Effects on the Course of the Reductive Acylation of Penicillin Sulfoxide Derived Sulfenates
Published online, 1st January, 1970
DOI: 10.3987/R-1981-10-1651
■ Substitutent Effects on the Course of the Reductive Acylation of Penicillin Sulfoxide Derived Sulfenates
Leilani V. Kapili, Michael S. Kellogg,* and Robert J. Martingano
*Central Research Division, Pfizer Inc., Eastern Point Road, Groton, Connecticut 06340, U.S.A.
Abstract
Reductive acylation of penicillanate sulfoxide derived sulfenates with trivalent phosphorous compounds and acetic anhydride has been shown to give β-lactam products resulting from either oxygen or sulfur transfer to phosphorous dependent on the substituent at the C-6 position of the penicillanate.
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