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Communication | Regular issue | Vol 16, No. 8, 1981, pp.1295-1299
Published online, 1st January, 1970
DOI: 10.3987/R-1981-08-1295
Synthesis of 5-Aryl-5,6,7,8-tetrahydrothiazolo[3,4-a]pyridinium Bromides

Takeshi Hara* and John C. Sheehan

*Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, U.S.A.


5,6,7,8-Tetrahydro-5-phenylthiazolo[3,4-a]pyridinium bromide (1a) and 5-(p-chlorophenyl)-5,6,7,8-tetrahydrothiazolo[3,4-a]pyridinium bromide (1b) have been synthesized with 4-(3-carboethoxypropyl)-thiazole (3) and/or 4-(4-phenyl-3-butenyl)thiazole (9a) or 4-[4-(p-chlorophenyl)-3-butenyl]thiazole (9b) as an intermediate.