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Communication | Regular issue | Vol 16, No. 6, 1981, pp.905-908
Published online, 1st January, 1970
DOI: 10.3987/R-1981-06-0905
Synthesis of Thromboxane A2 Analogue. (±)-(9,11),(11,12)-Dideoxa-(9,11a)-oxathromboxane A2

Tetsuji Kametani,* Toshio Suzuki, Akiko Tomino, Shinko Kamada, and Katsuo Unno

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

A synthesis of the thromboxane A2 analogue, (±)-(9, 11) ,(11, 12)-dideoxa-(9, 11a)-oxathromboxane A2 (TXA2) starting from the exo-adduct 3 of meleic anhydride and furan is described.