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Communication | Regular issue | Vol 14, No. 12, 1980, pp.1915-1920
Published online, 1st January, 1970
DOI: 10.3987/R-1980-12-1915
Aromatic Substitution Effects in the Aspidospermane-Eburnane Rearrangement of Indole Alkaloids

Guy Lewin, Yves Rolland, and Jacques Poisson*

*Centre d’Etudes Pharmaceutiques, C. N. R. S., E. R.. A. 317, 92290 Châtenay-Marabry, France


The influence of substitutions in aromatic part of indole alkaloids with aspidosperma skeleton on their rearrangement into products with eburnane-type structure is studied. Results are applied to vincamine derivatives.