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Communication | Regular issue | Vol 14, No. 11, 1980, pp.1735-1738
Published online, 1st January, 1970
DOI: 10.3987/R-1980-11-1735
A Simple Synthesis of Bicyclo[2.2.1]heptane System, a Key Potential Intermediate for Stable Prostaglandin H2 Analogue

Toshio Suzuki, Akiko Tomino, Yasuyuki Matsuda, Katsuo Unno, and Tetsuji Kametani*

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


A simple and efficient synthesis of 6-cyanomethyl-1-methoxycarbonylbicyclo[2.2.1]heptane system leading to stable prostaglandin H2 analogue is described.