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Communication | Regular issue | Vol 14, No. 10, 1980, pp.1441-1444
Published online, 1st January, 1970
DOI: 10.3987/R-1980-10-1441
The Use of Tetra-N-butylammonium Borohydride for the Reduction of Indoles to Indolines in Dichloromethane

Takeshi Wakamatsu,* Harumi Inaki, Akemi Ogawa, Masako Watanabe, and Yoshio Ban

*Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12 Nishi 6, Kita-ku, Sapporo, Hokkaido 060-0812, Japan

Abstract

Several indole compounds were reduced with tetra-n-butylammonium borohydride in dichloromethane to the corresponding indolines under mild conditions, in which solvent most of indole compounds are easily soluble.