Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Report | Regular issue | Vol 14, No. 8, 1980, pp.1135-1138
Published online, 1st January, 1970
DOI: 10.3987/R-1980-08-1135
The Demethylation of Aporphines with Sulfuric Acid

Luis Castedo,* Angel Rodriguez de Lera, José M. Saá, Rafael Suau, and Carmen Villaverde

*Departamento de Química Orgánica e Unidade Asociada al CSIC, Facultad de Quimica, Universidad de Santiago de Compostela, E-15706, Santiago de Compostela, Spain


Sulfuric acid at room temperature has been found a useful reagent for interconverting aporphine alkaloids by selective O-demethylation. This was controlled by electronic or steric effects.