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Communication | Regular issue | Vol 14, No. 6, 1980, pp.755-760
Published online, 1st January, 1970
DOI: 10.3987/R-1980-06-0755
Synthesis of 5-(Substituted alkyl)picolinic Acids, the Dopamine β-Hydroxylase Inhibitors. III

Koichi Miyano, Takeji Sakasai, and Hiroaki Hamano*

*Research Laboratories, Nippon-Kayaku Co. Ltd., 3-31-12, Shimo, Kita, Tokyo 115-0042, Japan

Abstract

Several 5-alkylpicolinic acids, dopamine β-hydroxylase inhibitors were synthesized from 2-cyclopropyl-5-cyclopropylcarbonylpyridine (I) as a suitable starting material.