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Communication | Regular issue | Vol 14, No. 6, 1980, pp.751-754
Published online, 1st January, 1970
DOI: 10.3987/R-1980-06-0751
Biogenetic-type Synthesis of Clivimine from Clivacetine

Shigeru Kobayashi,* Yasuhiro Imakura, Hideki Ishikawa, and Etsuko Sasakawa

*Faculty of Pharmaceutical Sciences, University of Tokushima, Sho-machi, Tokushima 770-8505, Japan

Abstract

The structures of clivacetine (1) and clivatine (4) were confirmed by the partial synthesis of clivacetine (1) from clivonine (2). Clivimine (3) was obtained by biogenetic-type synthesis from clivacetine (1), which seems to be a biosynthetic precursor of clivimine (3).