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Communication | Regular issue | Vol 14, No. 5, 1980, pp.631-633
Published online, 1st January, 1970
DOI: 10.3987/R-1980-05-0631
A Formal Total Symthesis of the Alkaloid Yohimbine

Ichiya Ninomiya,* Yukiko Tada, Okiko Miyata, and Takeaki Naito

*Kobe Women’s College of Pharmacy, Motoyamakita, Higashinad, Kobe, Hyogo 658, Japan


Photocyclization of the enamide (3a), which was readily prepared from harmalane and substituted benzoyl chloride, provided a simple preparation of the key intermediate (4a) for total synthesis of the alkaloid yohimbine.