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Communication | Regular issue | Vol 14, No. 4, 1980, pp.453-456
Published online, 1st January, 1970
DOI: 10.3987/R-1980-04-0453
An Approach to the Synthesis of the Non-tryptamine Moiety of Reserpine by Diels-Alder Reaction

Seiichi Takano,* Fumitaka Ito, and Kunio Ogasawara

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


Diels-Alder adduct 2 between furfural ethylene acetal 1 and maleic anhydride has been converted into the tricyclic acetal 10b which would be a promising intermediate for the construction of the non-tryptamine moiety of the Rauwolfia alkaloids, such as reserpine (13).