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Communication | Regular issue | Vol 14, No. 3, 1980, pp.267-270
Published online, 1st January, 1970
DOI: 10.3987/R-1980-03-0267
A Convenient Synthesis of Pyridazino[4,5-b]quinolines and Pyrrolo[3,4-b]quinolines

Yoshihisa Kurasawa* and Atsushi Takada

*School of Pharmaceutical Sciences, Kitasato University, Shirokane, Minato-ku, Tokyo 108-8641, Japan

Abstract

Pyridazino[4,5-b]quinolines were conveniently synthesized from the reaction of N-(1,2-bisethoxycarbonylvinyl)-o-aminoacetophenone with hydrazines, and 2,3-bishydrazinocarbonyl-4-methylquinolines were easily cyclized to pyrrolo[3,4-b]quinolines.